Lean, also known as purple drank, purp, sizzurp, syrup, wock or oil, and several other names, is a recreational drug beverage, prepared by mixing prescription strength cough or cold syrup containing codeine and promethazine with a soft drink. The beverage originated in Houston and is popular in hip hop culture, especially within the Southern ... Sep 14, 2018 · Codeine is a prescription opioid, which is used as a pain reliever, and promethazine is an antihistamine. Both drugs have sedative effects and can produce feelings of drowsiness, mild euphoria and ... Oct 10, 2022 · Initial dose: 15 to 60 mg orally up to every 4 hours as needed. Maximum dose: 360 mg in 24 hours. Comments: Initial doses should be individualized taking into account severity of pain, response, prior analgesic treatment experience, and risk factors for addiction, abuse, and misuse. Doses higher than 60 mg have not been shown to improve pain ... Codeine / Promethazine HCl 10 mg - 6.25 mg / 5 mL Syrup Bottle 16 oz. CV Akorn 50383080416. Call Us. Medical professionals, medical facility employees 855.571.2100. Need help with SupplyManager?The codeine in Promethazine VC with Codeine can cause newborns to experience withdrawal syndrome, which is life-threatening for infants. Withdrawal syndrome is a condition that develops when Promethazine VC with Codeine crosses through the placenta and causes the unborn baby to become dependent on the medication.Aug 1, 2023 · cough. darkened urine. darkening of the skin. diarrhea. difficult or trouble breathing. difficulty swallowing. dizziness. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position. fainting. Phenergan with Codeine (promethazine and codeine) is a combination of an antihistamine, sedative, anti-nausea drug, cough suppressant, pain reliever, and cough suppressant used to treat common cold symptoms and cough. Common side effects of Phenergan with Codeine include dizziness, restlessness, inability to sleep, palpitations, and changes in muscle tone and more. Withdrawal symptoms may ... Promethazine is an antihistamine that relieves watery eyes, itchy eyes /nose/throat, runny nose, and sneezing. Codeine is an opioid cough suppressant ( antitussive) that affects a certain part... after a dosage increase. if you are older. if you have an existing lung problem. The side effects of codeine are similar to those of other opioids, and include: constipation. headache or dizziness. fatigue or drowsiness (especially soon after a dose) loss of appetite, nausea and vomiting. Always take medicines exactly as prescribed your doctor.May 2, 2014 · Promethazine with codeine syrup is indicated for the temporary relief of coughs and upper respiratory tract symptoms related to allergies or the common cold. What is promethazine used for? Promethazine is an antihistamine, similar to products available over-the-counter like Benadryl, Claritin, Zyrtec, and Allegra. Antihistamines are typically ... Physical effects. Codeine taken at high doses could produce the following effects that can last 3-5 hours: drowsiness. headaches. slowed breathing. nausea and vomiting. smaller (constricted) pupils. feeling heavy in the arms and legs. severe itching or warm/hot sensation on the skin.Promethazine. Codeine is an effective pain reliever; however, it is addictive, may cause constipation, and its pain-relieving effects vary markedly between individuals. Codeine should only be used for pain relief... more. Promethazine may be used to relieve allergy symptoms and nausea. Sedation is the main side effect and it may interact with ... Schedule 5 (V) Drugs. The drug has a low potential for abuse relative to the drugs in schedule 4. The drug has a currently accepted medical use in treatment in the United States.Promethazine/codeine is an inexpensive drug used as a cough suppressant, a decongestant, and an antihistamine. It helps to stop or reduce coughing and congestion. It is more popular than comparable drugs. Promethazine/codeine is only available as a generic drug; all brands have been discontinued. Promethazine with codeine syrup is indicated for the temporary relief of coughs and upper respiratory tract symptoms related to allergies or the common cold. What is promethazine used for? Promethazine is an antihistamine, similar to products available over-the-counter like Benadryl, Claritin, Zyrtec, and Allegra. Antihistamines are typically ...Codeine is a narcotic pain reliever (analgesic) used to treat mild to moderately severe pain frequently combined with Tylenol or aspirin. Common side effects include itching, rash, stomach pain, constipation, shortness of breath, nausea, lightheadedness, and dizziness. Codeine is a controlled narcotic and it has the potential for abuse. Dependence and addiction can occur with codeine, even at ...Promethazine with codeine syrup is indicated for the temporary relief of coughs and upper respiratory tract symptoms related to allergies or the common cold. What is promethazine used for? Promethazine is an antihistamine, similar to products available over-the-counter like Benadryl, Claritin, Zyrtec, and Allegra. Antihistamines are typically ...Uses for Phenergan w/Codeine. Promethazine and codeine combination is used to relieve cough, runny or stuffy nose, sneezing, or other symptoms caused by allergies or the common cold. Promethazine is an antihistamine. It works by preventing the effects of a substance called histamine, which is produced by the body.Aug 1, 2023 · Adults and children 12 years of age and older—5 milliliters (mL) (1 teaspoonful) every 4 to 6 hours. Do not take more than 30 mL in 24 hours. Children 6 to 11 years of age—2.5 to 5 mL (0.5 to 1 teaspoonful) every 4 to 6 hours. Do not take more than 30 mL in 24 hours. Children younger than 6 years of age—Use is not recommended. Missed Dose Codeine and promethazine es una medicina combinada se usa para el tratamiento de los síntomas del resfrío o alergias como nariz mocosa, estornudos, y tos. Codeine and promethazine contiene una medicina opioide (narcótico) para la tos, y puede crear hábito. . Codeine and promethazine puede también usarse para fines no...FDA approved a REMS for codeine to ensure that the benefits outweigh the risk. The REMS may apply to one or more preparations of codeine and consists of the following: medication guide and elements to assure safe use. See the FDA REMS page ().Constipation. Itching. Slowed breathing. Changes in vision. Over long periods of time, codeine abuse can cause an increase in lung infections, bowel damage, sleep disorders, irregular heart rate, and even brain damage. Beyond the physical effects, drug addiction tends to have a profound impact on life satisfaction.Promethazine HCl and Codeine Phosphate Oral Solution exposes patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. Reserve Promethazine HCl and Codeine Phosphate Oral Solution for use in adult patients for whom the Jan 20, 2021 · Typical dosing for Robitussin AC (guaifenesin / codeine) Adults and children over 12 years old: The typical dose is 2 teaspoonfuls (10 mL) by mouth every 4 hours as needed. Children between 6 and 12 years old: The typical dose is 1 teaspoonful (5 mL) by mouth every 4 hours as needed. Children under 6 years old: Speak with your child's provider. Promethazine is a prescription cold medication used to treat various conditions, including nausea and vomiting. Codeine is a naturally occurring opiate that relieves pain. They are combined in promethazine-codeine cough syrup, a prescription medication used to alleviate symptoms of allergies or the common cold.A total of 486 drugs are known to interact with codeine / guaifenesin : 122 major drug interactions (477 brand and generic names) 361 moderate drug interactions (1496 brand and generic names) 3 minor drug interactions (7 brand and generic names) A total of 748 drugs are known to interact with codeine / promethazine : 181 major drug interactions ...Jan 10, 2021 · Promethazine is a phenothiazine medication that blocks the signals in your brain and body causing you to experience cold and allergy symptoms like a runny nose and sneezing. Codeine is an opioid medication that works in your brain to lessen your urge to cough. In the early 1990s, several studies reported the misuse of codeine and promethazine hydrochloride cough syrup. Since then, the combination of this pharmaceutical, together with sprite or alcohol, known on the streets as "purple drank" or "lean", has become a popular drug among rap singers who promot …Aug 27, 2009 · Each 5 mL (one teaspoonful), for oral administration contains: Promethazine hydrochloride 6.25 mg; codeine phosphate 10 mg. Alcohol 7%. Inactive Ingredients: Ascorbic acid, citric acid, FD&C ... Codeine: Narcotic analgesics, including codeine, exert their primary effects on the central nervous system and gastrointestinal tract. The analgesic ... Typical dosing for Robitussin AC (guaifenesin / codeine) Adults and children over 12 years old: The typical dose is 2 teaspoonfuls (10 mL) by mouth every 4 hours as needed. Children between 6 and 12 years old: The typical dose is 1 teaspoonful (5 mL) by mouth every 4 hours as needed. Children under 6 years old: Speak with your child's provider.Constipation. Itching. Slowed breathing. Changes in vision. Over long periods of time, codeine abuse can cause an increase in lung infections, bowel damage, sleep disorders, irregular heart rate, and even brain damage. Beyond the physical effects, drug addiction tends to have a profound impact on life satisfaction.Lean, also known as purple drank, purp, sizzurp, syrup, wock or oil, and several other names, is a recreational drug beverage, prepared by mixing prescription strength cough or cold syrup containing codeine and promethazine with a soft drink. The beverage originated in Houston and is popular in hip hop culture, especially within the Southern ... Phenergan with Codeine (promethazine and codeine) is a combination of an antihistamine, sedative, anti-nausea drug, cough suppressant, pain reliever, and cough suppressant used to treat common cold symptoms and cough. Common side effects of Phenergan with Codeine include dizziness, restlessness, inability to sleep, palpitations, and changes in muscle tone and more. Withdrawal symptoms may ... Aug 4, 2023 · Promethazine 6.25 mg/ Codeine 10 mg per 5 mL: Average effective dose: 5 mL orally every 4 to 6 hours as needed. Maximum dose: 30 mL (promethazine 37.5 mg; codeine: 60 mg) in 24 hours. Comments: Liquid preparations should be measured with an accurate milliliter measuring device. Uses: Temporary relief of coughs and upper respiratory symptoms ... May 22, 2023 · Independently, Codeine and Promethazine are both depressants that largely affect the nervous system, and when they’re combined, the result is intense and euphoric sedation. In larger quantities, lean has been found to induce hallucinations and lucid dreams or nightmares; some artists have claimed it to assist in their creative process. Codeine and promethazine es una medicina combinada se usa para el tratamiento de los síntomas del resfrío o alergias como nariz mocosa, estornudos, y tos. Codeine and promethazine contiene una medicina opioide (narcótico) para la tos, y puede crear hábito. . Codeine and promethazine puede también usarse para fines no... severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out. Side effects such as confusion and severe drowsiness may be more likely in older adults. Common promethazine side effects may include: drowsiness, dizziness; ringing in your ears;Aug 29, 2023 · Codeine cough suppressants like promethazine/codeine should only be an option for short-term use — and only in adults. This type of cough syrup is available by prescription. However, it is a controlled substance and habit-forming. Best cough medicine for kids The benefits of taking Promethazine VC/Codeine (promethazine, phenylephrine, and codeine) for a cough due to allergies, a cold, or other infection do not outweigh the risks in children. If your child has been given Promethazine VC/Codeine (promethazine, phenylephrine, and codeine) or if you have any questions, talk with your child's doctor.Acetaminophen/codeine oral solution. Each 5 mL of acetaminophen/codeine solution contains 12 mg of codeine and 120 mg of acetaminophen. The typical dose is 15 mL by mouth every 4 hours as needed. Do not take more than 3,000 mg to 4,000 mg of acetaminophen within a 24-hour period.Dec 13, 2022 · severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out. Side effects such as confusion and severe drowsiness may be more likely in older adults. Common promethazine side effects may include: drowsiness, dizziness; ringing in your ears; Codeine Dosage and Administration General Managing Opiate Therapy for Acute Pain. Optimize concomitant use of other appropriate therapies. When opiate analgesia required, use conventional (immediate-release) opiates in smallest effective dosage and for shortest possible duration, since long-term opiate use often begins with treatment of acute pain.Phenergan with Codeine (promethazine and codeine) is a combination of an antihistamine, sedative, anti-nausea drug, cough suppressant, pain reliever, and cough suppressant used to treat common cold symptoms and cough. Common side effects of Phenergan with Codeine include dizziness, restlessness, inability to sleep, palpitations, and changes in muscle tone and more. Withdrawal symptoms may ... Codeine Information. Codeine is an opioid pain reliever used to treat mild to moderately severe pain. It is also used, usually in combination with other medications, to reduce coughing. Codeine is ...Use Caution/Monitor. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Interaction more likely in certain predisposed pts. only. codeine and protriptyline both increase sedation. Use Caution/Monitor. promethazine and protriptyline both increase QTc interval.Codeine and promethazine es una medicina combinada se usa para el tratamiento de los síntomas del resfrío o alergias como nariz mocosa, estornudos, y tos. Codeine and promethazine contiene una medicina opioide (narcótico) para la tos, y puede crear hábito. . Codeine and promethazine puede también usarse para fines no...Physical effects. Codeine taken at high doses could produce the following effects that can last 3-5 hours: drowsiness. headaches. slowed breathing. nausea and vomiting. smaller (constricted) pupils. feeling heavy in the arms and legs. severe itching or warm/hot sensation on the skin.Promethazine Hydrochloride and Codeine Phosphate Syrup is a prescription medicine used to temporarily treat cough and upper respiratory symptoms that you can have with allergies or a common cold. Promethazine Hydrochloride and Codeine Phosphate Syrup contains 2 medicines, promethazine and codeine. Promethazine is an antihistamine.Initial dose: 15 to 60 mg orally up to every 4 hours as needed. Maximum dose: 360 mg in 24 hours. Comments: Initial doses should be individualized taking into account severity of pain, response, prior analgesic treatment experience, and risk factors for addiction, abuse, and misuse. Doses higher than 60 mg have not been shown to improve pain ...The benefits of taking Promethazine VC/Codeine (promethazine, phenylephrine, and codeine) for a cough due to allergies, a cold, or other infection do not outweigh the risks in children. If your child has been given Promethazine VC/Codeine (promethazine, phenylephrine, and codeine) or if you have any questions, talk with your child's doctor.Find patient medical information for promethazine oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. ... (such as codeine, hydrocodone), ...Aug 1, 2023 · Adults and children 12 years of age and older—5 milliliters (mL) (1 teaspoonful) every 4 to 6 hours. Do not take more than 30 mL in 24 hours. Children 6 to 11 years of age—2.5 to 5 mL (0.5 to 1 teaspoonful) every 4 to 6 hours. Do not take more than 30 mL in 24 hours. Children younger than 6 years of age—Use is not recommended. Missed Dose Promethazine with codeine syrup is indicated for the temporary relief of coughs and upper respiratory tract symptoms related to allergies or the common cold. What is promethazine used for? Promethazine is an antihistamine, similar to products available over-the-counter like Benadryl, Claritin, Zyrtec, and Allegra. Antihistamines are typically ...Promethazine with Codeine Oral Solution is a combination of codeine, an opioid agonist; and promethazine, a phenothiazine, indicated for the temporary relief of cough and upper respiratory symptoms associated with allergy or the common cold in patients 18 years of age and older.a liquid that you swallow – this contains 25mg of codeine in a 5ml spoonful. The usual dose of codeine is 15mg to 60mg. adults – one or two 30mg tablets, taken every 4 hours, up to a maximum of 8 tablets (240mg) in 24 hours. children (aged 12 to 17 years) – one or two 30mg tablets (or one or two 5ml spoonfuls of liquid), taken every 6 hours.Generic name: codeine / promethazine systemic Drug class: upper respiratory combinations. For consumers: dosage, interactions, side effects. For professionals: Prescribing Information. Expand current row for information about Hycodan Hycodan: 8.5Jan 20, 2023 · Codeine is a narcotic pain reliever (analgesic) used to treat mild to moderately severe pain frequently combined with Tylenol or aspirin. Common side effects include itching, rash, stomach pain, constipation, shortness of breath, nausea, lightheadedness, and dizziness. Codeine is a controlled narcotic and it has the potential for abuse. Dependence and addiction can occur with codeine, even at ... The codeine in Promethazine VC with Codeine can cause newborns to experience withdrawal syndrome, which is life-threatening for infants. Withdrawal syndrome is a condition that develops when Promethazine VC with Codeine crosses through the placenta and causes the unborn baby to become dependent on the medication.Apr 26, 2023 · codeine. Used for Pain. Codeine is an opioid pain medication that's taken by mouth and used to treat mild-to-moderate pain. Common side effects of codeine include constipation, itching, sleepiness, and dizziness. It's typically not a first-choice pain medication because it can lead to more serious harm, such as slowed breathing and addiction. Promethazine VC with Codeine Oral Solution is a combination of codeine, an opioid agonist; promethazine, a phenothiazine; and phenylephrine, an alpha-1 adrenergic receptor agonist, indicated for the temporary relief of cough and upper respiratory symptoms, including nasal congestion, associated with allergy or the common cold in patients 18 years of age and older.Promethazine HCl and Codeine Phosphate Oral Solution in adolescents 12 to 18 years of age who have other risk factors that may increase their sensitivity to the respiratory depressant effects of codeine. Promethazine and Respiratory Depression in Children Postmarketing cases of respiratory depression, including fatalities have been reported with Find patient medical information for acetaminophen-codeine oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.Codeine Information. Codeine is an opioid pain reliever used to treat mild to moderately severe pain. It is also used, usually in combination with other medications, to reduce coughing. Codeine is ...Find patient medical information for promethazine oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. ... (such as codeine, hydrocodone), ...The most frequently reported codeine-containing medicines in the cases were acetaminophen with codeine used for pain, and promethazine with codeine (with or without phenylephrine) used for cough ... Feb 13, 2023 · Codeine is a medication used in the management and treatment of chronic pain. It is in the opioid class of medications. This activity outlines the indications, action, and contraindications for codeine as a valuable agent in treating chronic pain and off-label use in cough, persistent diarrhea, and restless leg syndrome. In addition, this activity will highlight the mechanism of action ... Oct 24, 2016 · Houston’s relationship with “lean,” or codeine-promethazine, goes back to at least the 1960s, when blues musicians would mix Robitussin with alcohol. These musicians lived in the same ... Codeine is a prescription opioid, which is used as a pain reliever, and promethazine is an antihistamine. Both drugs have sedative effects and can produce feelings of drowsiness, mild euphoria and ...Codeine / Promethazine HCl 10 mg - 6.25 mg / 5 mL Syrup Bottle 16 oz. CV Akorn 50383080416. Call Us. Medical professionals, medical facility employees 855.571.2100. Need help with SupplyManager? Codeine is used to relieve mild to moderately severe pain, and it belongs to the drug class of opioid analgesics. Codeine has also been prescribed to prevent coughing, though the antitussive administration is most often in liquid formulations and in conjunction with other medications. ( 1, 2) The hepatic CYP2D6 enzyme metabolizes a quarter of ...Generic Name (S): codeine-guaifenesin. Warnings: This medication has a risk for abuse and addiction, which can lead to overdose and death. This medication may also cause severe, possibly fatal ...Aug 1, 2023 · Adults and children 12 years of age and older—5 milliliters (mL) (1 teaspoonful) every 4 to 6 hours. Do not take more than 30 mL in 24 hours. Children 6 to 11 years of age—2.5 to 5 mL (0.5 to 1 teaspoonful) every 4 to 6 hours. Do not take more than 30 mL in 24 hours. Children younger than 6 years of age—Use is not recommended. Missed Dose Generic name: codeine / promethazine systemic Drug class: upper respiratory combinations. For consumers: dosage, interactions, side effects. For professionals: Prescribing Information. Expand current row for information about Hycodan Hycodan: 8.5Generic Name (S): codeine-guaifenesin. Warnings: This medication has a risk for abuse and addiction, which can lead to overdose and death. This medication may also cause severe, possibly fatal ...Generic Name (S): codeine sulfate. Codeine has a risk for abuse and addiction, which can lead to overdose and death. Codeine may also cause severe, possibly fatal, breathing problems. To lower ...For all patients taking this drug: This drug has an opioid drug in it. Opioid drugs can put you at risk for addiction, abuse, and misuse. Misuse or abuse of this drug can lead to overdose and death. If you have questions, talk with your doctor. This drug may cause very bad and sometimes deadly breathing problems.May 5, 2020 · Promethazine with Codeine Oral Solution is a combination of codeine, an opioid agonist; and promethazine, a phenothiazine, indicated for the temporary relief of cough and upper respiratory symptoms associated with allergy or the common cold in patients 18 years of age and older. Aug 29, 2023 · Codeine cough suppressants like promethazine/codeine should only be an option for short-term use — and only in adults. This type of cough syrup is available by prescription. However, it is a controlled substance and habit-forming. Best cough medicine for kids Promethazine with codeine syrup is indicated for the temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold. CONTRAINDICATIONS. The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric patients less than 6 years of age, because the combination may cause ...Find patient medical information for promethazine oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. ... (such as codeine, hydrocodone), ...
Codeine is also available in conjunction with the anti-nausea medication promethazine in the form of a syrup. Brand named as Phenergan with Codeine or in generic form as promethazine with codeine, it began to be mixed with soft drinks in the 1990s as a recreational drug, called 'syrup', 'lean', or ' purple drank '. [61]. Qdzjwlow
Apr 15, 2023 · Codeine and morphine were detected in the milk of both subjects with peak codeine levels in milk occurring 1 hour after the dose. The peak codeine milk level was 455 mcg/L in the first subject and about 450 to 550 mcg/L in the second. The half-life of codeine in breastmilk was 2.5 hours. Morphine milk levels were 16 mcg/L and 9 mcg/L 1 hour ... Codeine is an effective pain reliever; however, it is addictive, may cause constipation, and its pain-relieving effects vary markedly between individuals. Codeine should only be used for pain relief when other simpler analgesics, such as acetaminophen or ibuprofen, are not appropriate. 5. Tips. May be taken with or without food.Generic name: promethazine hydrochloride and codeine phosphate Dosage form: oral solution Drug class: Upper respiratory combinations Medically reviewed by Drugs.com. Last updated on Jan 1, 2022. On This Page Indications and Usage Dosage and Administration Dosage Forms and Strengths Contraindications Warnings and PrecautionsCough and Cold Medicines • May 2014 • Page 2 ! Drinking!promethazine(codeinecough syrup!mixed!with!soda!(a!combination! calledsyrup,sizzurp,purpledrank,barre,Promethazine 6.25 mg/ Codeine 10 mg per 5 mL: Average effective dose: 5 mL orally every 4 to 6 hours as needed. Maximum dose: 30 mL (promethazine 37.5 mg; codeine: 60 mg) in 24 hours. Comments: Liquid preparations should be measured with an accurate milliliter measuring device. Uses: Temporary relief of coughs and upper respiratory symptoms ...Promethazine with codeine syrup is indicated for the temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold. CONTRAINDICATIONS. The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric patients less than 6 years of age, because the combination may cause ...Promethazine is an antihistamine that relieves watery eyes, itchy eyes /nose/throat, runny nose, and sneezing. Codeine is an opioid cough suppressant ( antitussive) that affects a certain part...Codeine is a drug in some prescription pain medicines. It is in the class of drugs known as opioids, which refers to any synthetic, semisynthetic, or natural drug that has morphine-like properties. Codeine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose. This ...Generic name: promethazine hydrochloride and codeine phosphate Dosage form: oral solution Drug class: Upper respiratory combinations Medically reviewed by Drugs.com. Last updated on Jan 1, 2022. On This Page Indications and Usage Dosage and Administration Dosage Forms and Strengths Contraindications Warnings and PrecautionsFeb 4, 2021 · Codeine (3-methylmorphine) is an alkaloid prepared from the methylation of morphine derived from poppy seeds ( Papaver somniferum) [ 1 ]. It is used to manage mild to moderate pain, including chronic cancer pain, and has antitussive, antistress, and antidiarrheal properties [ 2, 3, 4 ]. In the body, a small amount of codeine is metabolized to ... Anecdotal promethazine misuse/abuse reports have been confirmed by European Monitoring Agency data. Promethazine misuse/abuse appears to be an alarming issue, being associated with drug-related fatalities. Thus, healthcare professionals should be warned about a possible misuse of promethazine and be …Promethazine VC with Codeine Oral Solution is a combination of codeine, an opioid agonist; promethazine, a phenothiazine; and phenylephrine, an alpha-1 adrenergic receptor agonist, indicated for the temporary relief of cough and upper respiratory symptoms, including nasal congestion, associated with allergy or the common cold in patients 18 years of age and older.Promethazine Hydrochloride and Codeine Phosphate Syrup is a prescription medicine used to temporarily treat cough and upper respiratory symptoms that you can have with allergies or a common cold. Promethazine Hydrochloride and Codeine Phosphate Syrup contains 2 medicines, promethazine and codeine. Promethazine is an antihistamine. a liquid that you swallow – this contains 25mg of codeine in a 5ml spoonful. The usual dose of codeine is 15mg to 60mg. adults – one or two 30mg tablets, taken every 4 hours, up to a maximum of 8 tablets (240mg) in 24 hours. children (aged 12 to 17 years) – one or two 30mg tablets (or one or two 5ml spoonfuls of liquid), taken every 6 hours.codeine/promethazine systemic. Drug class: upper respiratory combinations. Codeine/promethazine systemic is used in the treatment of: Cough; codeine/pseudoephedrine systemic. Brand names: Cycofed, Nucodine, Codar D, Nucofed, EndaCof-DC Drug class: upper respiratory combinations. Codeine/pseudoephedrine systemic is used in the treatment of:.